Influence of hepatitis G virus infection on liver disease

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Hepatitis G virus infection in chronic liver disease.

BACKGROUND The hepatitis G virus (HGV), a recently identified member of the Flaviviridae family, can cause chronic infection in man but the role of this agent in chronic liver disease is poorly understood. AIMS To evaluate the prevalence and meaning of HGV infection in a large series of patients with chronic liver disease. SUBJECTS Two hundred volunteer blood donors, 179 patients with chron...

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Liver histology in co-infection of hepatitis C virus (HCV) and hepatitis G virus (HGV).

As little is known about liver histology in the co-infection of hepatitis C virus (HCV) and hepatitis G virus (HGV), HGV RNA was investigated in 46 blood donors with hepatitis C, 22 of them with liver biopsy: co-infection HCV / HGV (n = 6) and HCV isolated infection (n = 16). Besides staging and grading of inflammation at portal, peri-portal and lobular areas (Brazilian Consensus), the fibrosis...

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Evaluation of miR-101 Level in Patients with Chronic Hepatitis B Virus Infection and Liver Cirrhosis

ABSTRACT        Background and Objective: MiRNAs are small RNAs that are expressed in most eukaryotes, and can regulate gene expression by attaching to the 3’ end of target mRNA. MicroRNA-101 (miR-101) post-transcriptional regulation is important for host-virus interactions. In addition, miR-101 has a tumor suppressive role in liver cancer and metastasis, an...

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Hepatitis B Virus Infection, MicroRNAs and Liver Disease

Hepatitis B virus (HBV) attacks the liver and can cause both acute as well as chronic liver diseases which might lead to liver cirrhosis and hepatocellular carcinoma. Regardless of the availability of a vaccine and numerous treatment options, HBV is a major cause of morbidity and mortality across the world. Recently,microRNAs (miRNAs) have emerged as important modulators of gene function. Studi...

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Hepatitis B virus and hepatitis C virus co-infection: additive players in chronic liver disease?

Hepatitis B virus (HBV) and hepatitis C virus (HCV) share modes of transmission and their combined infection is a fairly frequent occurrence particularly in areas where the two viruses are endemic and among subjects with a high risk of parenteral infections. Moreover, the number of coinfected patients is likely higher than is usually thought. In fact, many studies have shown that HBV genomes ma...

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ژورنال

عنوان ژورنال: European Journal of Clinical Microbiology & Infectious Diseases

سال: 1997

ISSN: 0934-9723,1435-4373

DOI: 10.1007/bf01700559